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衰老研究中常用大鼠品系的死亡率和生长特性。

Mortality and growth characteristics of rat strains commonly used in aging research.

作者信息

Masoro E J

出版信息

Exp Aging Res. 1980 Jun;6(3):219-33. doi: 10.1080/03610738008258359.

Abstract

In choosing an experimental animal for the study of aging, the investigator should have knowledge of certain basic characteristics of the animal. Of particular importance are longevity and growth. This review aims to provide available data on the mortality and growth characteristics of rat strains commonly used in aging research. In addition, the influences of nutrition and housing conditions on these characteristics are described and discussed. Finally, the usefulness of rats as models for the study of nutrition and aging is considered.

摘要

在选择用于衰老研究的实验动物时,研究者应了解该动物的某些基本特征。其中尤为重要的是寿命和生长情况。本综述旨在提供有关衰老研究中常用大鼠品系的死亡率和生长特征的现有数据。此外,还描述并讨论了营养和饲养条件对这些特征的影响。最后,探讨了大鼠作为营养与衰老研究模型的实用性。

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