Pastukhov Iu F
Fiziol Zh SSSR Im I M Sechenova. 1980 May;66(5):739-45.
Comparison of effects of catecholamines (noradrenaline, adrenaline, and isopropyl-noradrenaline) on oxygen consumption and body temperature and study of influence of beta- and alpha-adrenergic blocking agents (poropranolol and phentolamine) on their calorigenic effects in cold- and warm-adapted rats revealed that affinity of propranolol and all the catecholamines to beta-adrenoreceptors is enhanced. Influence of propranolol on the cold thermogenesis involves thermoregulatory metabolism decrease in warm-adapted rats and additional (compensatory) increase of thermoregulatory electrical muscle activity in cold-adapted rats. The sympathetic regulation of heat production and its changes at prolonged cold adaptation seem to be mainly of beta-adrenergic nature.
比较儿茶酚胺（去甲肾上腺素、肾上腺素和异丙基去甲肾上腺素）对氧消耗和体温的影响，并研究β-和α-肾上腺素能阻断剂（普萘洛尔和酚妥拉明）对冷适应和热适应大鼠产热效应的影响，结果显示普萘洛尔与所有儿茶酚胺对β-肾上腺素能受体的亲和力增强。普萘洛尔对冷适应性产热的影响涉及热适应大鼠体温调节代谢的降低以及冷适应大鼠体温调节性肌肉电活动的额外（代偿性）增加。产热的交感神经调节及其在长期冷适应时的变化似乎主要是β-肾上腺素能性质的。
