移行细胞研究。I. 大鼠骨髓在缺氧及恢复过程中的动力学变化。
Studies on transitional cells. I. Kinetic changes in rat bone marrow during hypoxia and rebound.
作者信息
Yoffey J M, Yaffe P
出版信息
J Anat. 1980 Mar;130(Pt 2):333-40.
Kinetic changes have been studied in the transitional cells of the marrow in normal, hypoxic (0.5 atm) and rebound rats. Suspensions of marrow cells were incubated with tritiated thymidine for 1 hour, and the percentage of labelled transitionals of all sizes, as well as of large transitionals, was couinted in radioautographs. From a normal labelling index of 55.4% +/- 6.0089 there is an initial fall after 1 day of hypoxia, followed by a significant rise to 69.233 +/- 2.8263% on day 3, when erythropoiesis is at its peak. This is followed by a sharp fall to a low level of 35% on day 2 of rebound, when erythropoiesis is depressed, returning to normal by day 7. The highest labelling index is found in the large transitional cells.
已经对正常、低氧（0.5个大气压）和恢复过程中的大鼠骨髓中的过渡细胞的动力学变化进行了研究。将骨髓细胞悬液与氚标记的胸腺嘧啶核苷一起孵育1小时，并在放射自显影片中计数所有大小的标记过渡细胞以及大过渡细胞的百分比。正常标记指数为55.4%±6.0089，低氧1天后开始下降，随后在第3天显著上升至69.233%±2.8263%，此时红细胞生成达到峰值。随后在恢复的第2天急剧下降至35%的低水平，此时红细胞生成受到抑制，到第7天恢复正常。最高标记指数出现在大过渡细胞中。
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