O'Leary M R, Donovan D M, Chaney E F, O'Leary D E
J Nerv Ment Dis. 1980 Aug;168(8):475-80. doi: 10.1097/00005053-198008000-00005.
The present study investigated the relationship of a multivariate classification of alcoholic patients based upon Minnesota Multiphasic Personality Inventory profiles taken at admission to psychopathology and drinking behavior at a 6- to 12-month follow-up interval. It was found that a subtype of patients characterized as psychoneurotic, with reactive anxiety and/or depression, evidenced significantly higher levels of psychopathology at follow-up than the remaining three subtypes. Furthermore, this subtype demonstrated higher levels of physical, social, and psychological impairment from post-treatment drinking episodes. No differences were found among the four subtypes with respect to outpatient therapists' ratings of personality change and adjustment. The findings suggest that such a multivariate classification of Minnesota Multiphasic Personality Inventory profiles has predictive utility. The results also suggest that the present subtypes would be useful in investigating the potential utility of differential therapeutic intervention strategies for different patients.
本研究调查了根据入院时明尼苏达多相人格调查表（MMPI）剖析图对酒精依赖患者进行的多变量分类与6至12个月随访期的精神病理学和饮酒行为之间的关系。结果发现，一种以精神神经症为特征、伴有反应性焦虑和/或抑郁的患者亚型，在随访时的精神病理学水平显著高于其余三种亚型。此外，该亚型在治疗后饮酒发作导致的身体、社会和心理损害方面表现出更高的水平。在门诊治疗师对人格改变和适应的评分方面，这四种亚型之间未发现差异。研究结果表明，这种基于MMPI剖析图的多变量分类具有预测效用。结果还表明，目前的亚型对于研究针对不同患者的差异化治疗干预策略的潜在效用将是有用的。
