Glucose tolerance in the heavy-for-date neonate: a pilot study.

Intravenous glucose tolerance tests were performed on 12 infants with birth-weights above the 95th centile (corrected for maternal height, weight and social class and for the gestation, sex and birth rank of the infant). In 4 infants the glucose disappearance rate (kt) was abnormally high (> 2.05), but glucose tolerance and birth weight were not correlated. However, enhanced glucose tolerance was significantly and positively correlated with obesity in the infant. Although these infants are biochemically abnormal, there is no evidence that this abnormality constitutes a clinical hazard.