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雄性促进未成熟小鼠中孕马血清促性腺激素诱导排卵的遗传和激素方面

Genetic and hormonal aspects of male facilitation of PMSG-induced ovulation in immature mice.

作者信息

Ho H, Wilson J R

出版信息

J Reprod Fertil. 1980 May;59(1):57-61. doi: 10.1530/jrf.0.0590057.

DOI:10.1530/jrf.0.0590057
PMID:7401046
Abstract

Immature female mice of the SWR/J and C3H/Ibg strains pretreated with PMSG showed higher incidence of ovulation when exposed to males of the same strain than did those kept isolated after weaning. Females of the C57BL/6Ibg strain were not affected. The numbers of eggs ovulated were also greater in SWR and C3H females than in the C57 females. When SWR/J females were killed after exposure to males for 2, 4 or 6 h, there was a 6-fold increase in LH levels at 6 h compared to values in isolated controls. It is suggested that adult male mice of some strains provide a stimulus which promotes release of LH in the immature female.

摘要

用孕马血清促性腺激素(PMSG)预处理的SWR/J和C3H/Ibg品系未成熟雌性小鼠,与断奶后单独饲养的小鼠相比,在接触同品系雄性时排卵发生率更高。C57BL/6Ibg品系的雌性不受影响。SWR和C3H雌性小鼠排出的卵子数量也比C57雌性小鼠多。当SWR/J雌性小鼠在接触雄性2、4或6小时后处死时,与单独饲养的对照组相比,6小时时促黄体生成素(LH)水平增加了6倍。提示某些品系的成年雄性小鼠提供了一种刺激,可促进未成熟雌性小鼠促黄体生成素的释放。

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