Brettschneider F, Goldstein P, Baer D, Kimball A, London R
J Reprod Med. 1980 Jul;25(1):10-3.
The importance of a laboratory test, especially when used as a screening procedure, is its ability to accurately provide information which can be used in the clinical management of patients. The fetal acceleration determination (FAD) has been utilized by many clinical obstetric services to assess the fetus at risk and to avoid the cumbersome and expensive oxytocin challenge test (OCT). In an effort to determine the usefulness of this modality in assessing the high-risk obstetric patient, a retrospective study of FADs was performed on 264 patients. All the tests were performed within one week of delivery. Fetal outcome was measured by Apgar scores, fetal morbidity and mortality and length of nursery stay. Chi square row by column contingency analysis was performed, and Bayes theorem was applied to our data to predict FAD specificity. The probability of false-positive and false-negative tests was high, and no correlation with outcome was observed. Analysis of these data indicates that the FAD is of limited value in identifying the fetus at risk.
实验室检查的重要性,尤其是用作筛查程序时,在于其准确提供可用于患者临床管理的信息的能力。许多临床产科服务机构已采用胎儿加速测定(FAD)来评估有风险的胎儿,并避免繁琐且昂贵的催产素激惹试验(OCT)。为了确定这种方法在评估高危产科患者中的实用性,对264例患者的FAD进行了回顾性研究。所有检查均在分娩前一周内进行。通过阿氏评分、胎儿发病率和死亡率以及新生儿住院时间来衡量胎儿结局。进行了卡方列联分析,并将贝叶斯定理应用于我们的数据以预测FAD特异性。假阳性和假阴性检查的概率很高,且未观察到与结局的相关性。对这些数据的分析表明,FAD在识别有风险的胎儿方面价值有限。