西咪替丁所致白细胞减少症
Leukopenia with cimetidine.
作者信息
Iyer S K, Chandrasekhara K L
出版信息
J Natl Med Assoc. 1980 Aug;72(8):805-6.
Abstract
A case of leukopenia associated with cimetidine therapy is reported. The patient had sarcoid cirrhosis with portal hypertension. Cimetidine therapy was instituted for upper gastrointestinal bleeding due to gastritis, resulted in leukopenia, and was reversed on discontinuation of therapy.
摘要
报告了1例与西咪替丁治疗相关的白细胞减少症病例。该患者患有结节病性肝硬化伴门静脉高压。因胃炎导致上消化道出血而开始使用西咪替丁治疗，结果出现白细胞减少，停药后白细胞减少情况逆转。
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本文引用的文献
1
Antacid versus cimetidine in preventing acute gastrointestinal bleeding. A randomized trial in 75 critically ill patients.抗酸剂与西咪替丁预防急性胃肠道出血的比较。一项针对75例危重症患者的随机试验。
N Engl J Med. 1980 Feb 21;302(8):426-30. doi: 10.1056/NEJM198002213020802.
2
Cimetidine and hematologic effects.西咪替丁与血液学效应。
Ann Intern Med. 1979 Nov;91(5):795. doi: 10.7326/0003-4819-91-5-795.
3
Association of cimetidine and bone-marrow suppression in man.西咪替丁与人体骨髓抑制的关联。
Dig Dis Sci. 1979 Sep;24(9):730. doi: 10.1007/BF01314472.
4
Bone-marrow suppression associated with cimetidine.
Ann Intern Med. 1979 Oct;91(4):580. doi: 10.7326/0003-4819-91-4-580.
5
Cimetidine and granulocytopenia.西咪替丁与粒细胞减少症
Ann Intern Med. 1979 Feb;90(2):264-5. doi: 10.7326/0003-4819-90-2-264.
6
Thrombocytopenia with cimetidine therapy.西咪替丁治疗所致血小板减少症
N Engl J Med. 1979 Apr 12;300(15):864. doi: 10.1056/nejm197904123001521.
7
Cimetidine and bone-marrow toxicity.西咪替丁与骨髓毒性。
Lancet. 1977 Sep 10;2(8037):555-6. doi: 10.1016/s0140-6736(77)90684-5.
8
Marrow suppression and intravenous cimetidine.
Lancet. 1978 May 6;1(8071):987. doi: 10.1016/s0140-6736(78)90272-6.
9
Agranulocytosis four months after cimetidine therapy.西咪替丁治疗四个月后发生粒细胞缺乏症。
Lancet. 1977 Aug 6;2(8032):294-5. doi: 10.1016/s0140-6736(77)90973-4.
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