Esplugas E, Amer R, Barthe J E, Jara F
Med Clin (Barc). 1980 Jul 15;75(3):112-4.
Associated coronary atherosclerosis in patients with rheumatic valvular heart disease is an important finding under prognostic and therapeutic viewpoints. Selective coronary angiography was carried out in 300 patients with rheumatic valvular disease (157 cases with associated mitral and aortic lesions; 57 cases with aortic regkurgitation; 35 cases with aortic stenosis; 31 cases with mitral stenosis, and 20 cases with mitral regurgitation). Significant coronary atherosclerosis occurs in 11 percent of all patients. The distribution of the lesions was as follows: anterior descending artery (56 percent); right coronary artery (47 percent); circumflex artery (28 percent); marginal artery (22 percent); oblique branches (19 percent), and common left trunk (3 percent). Lesions in the common left trunk were only present in association with aortic regurgitation. Fourty-four percent of patients with significant atherosclerosis showed multiple lesions, and there was a distal coronary tree appropriated to coronary bypass in 78 percent of the cases. The distribution of significant coronary lesions in patients with rheumatic valvular heart disease is similar to that observed in patients with ischemic heart disease. The frequent finding, however, of a short common left trunk and/or a left coronary prevalence in patients with aortic lesions is stressed under diagnostic and therapeutic viewpoints.
风湿性心脏瓣膜病患者合并冠状动脉粥样硬化,从预后和治疗角度来看是一项重要发现。对300例风湿性瓣膜病患者进行了选择性冠状动脉造影(其中157例合并二尖瓣和主动脉病变;57例主动脉瓣关闭不全;35例主动脉瓣狭窄;31例二尖瓣狭窄;20例二尖瓣反流)。所有患者中11%出现显著冠状动脉粥样硬化。病变分布如下:前降支(56%);右冠状动脉(47%);回旋支(28%);钝缘支(22%);斜支(19%);左主干(3%)。左主干病变仅与主动脉瓣关闭不全相关。44%有显著动脉粥样硬化的患者表现为多发病变,78%的病例有适合冠状动脉搭桥的远端冠状动脉树。风湿性心脏瓣膜病患者显著冠状动脉病变的分布与缺血性心脏病患者相似。然而,从诊断和治疗角度强调,主动脉病变患者常出现短左主干和/或左冠状动脉优势。