Rager G
Naturwissenschaften. 1980 Jun;67(6):280-7. doi: 10.1007/BF01153497.
Recent evidence indicates that the retinotectal projection has a field-to-field rather than a point-to-point precision. Therefore, individual fibres can vary their relative position in the fibre pathway to some extent. In addition it is not necessary that retinotopy is maintained throughout the whole pathway; transformations may also occur. In fact, in the chick embryo outgrowing retinal fibres maintain not an absolute but only a high degree of order. Transformations occur at the entrance to the optic nerve and probably also right behind the chiasm. The origin of the map is determined by the fact that central retinal fibres which are formed first connect to tectal neurons near the centre of the optic tectum where neurons mature first. There they immediately invade the cellular tectal layers and form functional synapses soon after. Supernumerary fibres degenerate.
最近的证据表明,视网膜 - 顶盖投射具有场对场而非点对点的精确性。因此,单个纤维在纤维通路中的相对位置可以在一定程度上有所变化。此外,在整个通路中保持视网膜拓扑结构并非必要;也可能会发生转换。事实上,在鸡胚中,生长中的视网膜纤维保持的不是绝对的而是高度的有序性。在视神经入口处以及可能在视交叉后方紧接着就会发生转换。图谱的起源取决于这样一个事实,即最早形成的中央视网膜纤维连接到视神经顶盖中心附近的顶盖神经元,那里的神经元最早成熟。它们在那里立即侵入顶盖细胞层,并在不久后形成功能性突触。多余的纤维会退化。