Gezernik W, Schmaman A, Chappell J S
S Afr Med J. 1980 Feb 2;57(5):151-4.
The toxicity of ferrous sulphate is discussed, with particular reference to fibrosis and stricturing of the stomach. This does not occur in every case, but occasionally, in spite of adequate treatment, ferrous sulphate produces local damage similar to that caused by acid. Endoscopy and barium studies are mandatory to assess the damage, and repeated checks should be undertaken, since late changes may take place as much as 6 years after ingestion. Gastrectomy is often necessary when severe scarring and fibrosis have resulted in damage to the stomach. The need for long-term follow-up of these patients is an important aspect of treatment.
讨论了硫酸亚铁的毒性，特别提及胃纤维化和狭窄。并非每种情况都会发生这种情况，但偶尔，尽管进行了充分治疗，硫酸亚铁仍会产生与酸所造成的类似局部损伤。必须进行内镜检查和钡剂检查以评估损伤情况，并且应进行反复检查，因为摄入后长达6年可能会出现晚期变化。当严重瘢痕形成和纤维化导致胃损伤时，通常需要进行胃切除术。对这些患者进行长期随访是治疗的一个重要方面。
