Fedorova T M, Rysiukova L N, Abilova G A
Zh Evol Biokhim Fiziol. 1980 May-Jun;16(3):222-7.
Studies have been made on the kinetics of the effect of DNAse I on nuclear DNA from the brain cortex, liver, spleen and kidney of albino rats. In all the nuclei studied, two DNA sites revealed which especially differ in the rate of their splitting. The share of rapidly splitted DNA amounts in the nuclei of the kidney and brain cortex up to 30%, in those of the liver and spleen -- about 25%. These findings are discussed in relation to the data available on the share of transcribed chromatin in the same tissues obtained by hybridization with nuclear RNA. For the brain and liver this method yields the same values, whereas for the spleen and kidney this test yields significantly lower values, i. e. about 10%.
已经对白化大鼠大脑皮层、肝脏、脾脏和肾脏的核DNA进行了DNA酶I作用动力学的研究。在所有研究的细胞核中，发现了两个DNA位点，它们在分裂速率上有特别的差异。在肾脏和大脑皮层的细胞核中，快速分裂的DNA占比高达30%，在肝脏和脾脏的细胞核中约为25%。结合通过与核RNA杂交获得的相同组织中转录染色质占比的现有数据，对这些发现进行了讨论。对于大脑和肝脏，这种方法得出的值相同，而对于脾脏和肾脏，该测试得出的值明显较低，即约10%。
