Stellpflug H, Wickings E J, Nieschlag E
Prakt Anaesth. 1978 Dec;13(6):483-8.
Before, during and after gynaecological operations performed either in electroacupuncture or enflurane anaesthesia plasma-cortisol levels were determined and compared to each other. During stimulation and operation plasma-cortisol increased continuously, indicating elevated sympathetic tone, whereas with enflurane anaesthesia plasma-cortisol levels were markedly lower. Postoperatively after electroacupuncture cortisol levels decreased, and rose again with the onset of pain. After enflurane anaesthesia cortisol levels increased continuously for a period of more than 90 min. Because of the strong correlation between degree of stress and plasma-cortisol level, our results demonstrate surgery under electroacupuncture analgesia to cause a stress greater than that during enflurane anaesthesia. The changes in cortisol levels were observed during stabilized cardiovascular conditions. Conditions varying plasma-cortisol levels too, are discussed.
在妇科手术前、手术期间和手术后,分别测定了接受电针麻醉和安氟醚麻醉患者的血浆皮质醇水平,并进行了对比。在刺激和手术过程中,电针麻醉组患者的血浆皮质醇持续上升,表明交感神经紧张度升高;而安氟醚麻醉组患者的血浆皮质醇水平则明显较低。电针麻醉术后,皮质醇水平下降,但随着疼痛的出现又再次上升。安氟醚麻醉术后,皮质醇水平在90多分钟内持续上升。由于应激程度与血浆皮质醇水平之间存在密切关联,我们的研究结果表明,电针镇痛下的手术所造成的应激大于安氟醚麻醉下的手术。本研究在心血管状况稳定的情况下观察了皮质醇水平的变化。文中还讨论了其他会使血浆皮质醇水平发生变化的情况。