[Ultrastructure of gastric parietal glandulocytes in experimental hyper- and hypothyroidism].

In 212 male rats (200-250 g) ultrastructure of gastric parietal glandulocytes has been studied at various levels of the thyroid hormones in the organism. At experimentally produced hyperthyrosis a definite direct dependence has been noted to exist between the developmental stage of mitochondrial membranes (cristae), mitochondrial enzymes activity and the level of hydrochloride acid secretion. At hypothyrosis, the gastric parietal cells have signs of low differentiation--large number of cisterns in the granular cytoplasmic network and lack of tubulovesicles are noted.