Siqueira M G, Rojas R A, Sturion D J
Arq Neuropsiquiatr. 1980 Mar;38(1):18-23. doi: 10.1590/s0004-282x1980000100003.
The authors present a critical analysis of the various methods of experimental production of aneurysms and report their own method in which saccular aneurysms were produced at the bifurcation of the common carotid artery in dogs with vein patch grafts. The objective point of this study was the creation of an experimental model to evaluate the efficacy of a therapeutic procedure. These aneurysms have a low incidence of thrombosis and a tendency to enlarge and to become spherical. They closely simulate the saccular aneurysms developing spontaneously in the cerebral arteries of man, and as such are useful models for experimental purposes.
作者对动脉瘤实验制作的各种方法进行了批判性分析,并报告了他们自己的方法,即在狗的颈总动脉分叉处用静脉补片移植制作囊状动脉瘤。本研究的客观目的是创建一个实验模型以评估一种治疗方法的疗效。这些动脉瘤血栓形成发生率低,有扩大并呈球形的趋势。它们与人类脑动脉中自发形成的囊状动脉瘤非常相似,因此是用于实验目的的有用模型。