石棉工人喉部的石棉小体含量。五例研究。

Asbestos body content of the larnyx in asbestos workers. A study of five cases.

作者信息

Roggli V L, Greenberg S D, McLarty J L, Hurst G A, Spivey C G, Heiger L R

出版信息

Arch Otolaryngol. 1980 Sep;106(9):533-5. doi: 10.1001/archotol.1980.00790330013006.

DOI:10.1001/archotol.1980.00790330013006

Abstract

Occupational exposure to asbestos has been epidemiologically associated with carcinoma of the larynx; however, no search for or quantitation of laryngeal asbestos bodies has been performed. This report concerns an autopsy study of five patients with occupational asbestos exposure and proven asbestos-associated pulmonary disease in whom histologic sections of the larynx were examined and a digestion-concentration technique was used to isolate and quantitate the asbestos bodies in the remaining laryngeal tissues. No dysplastic epithelial changes were present in the mucosa. Asbestos bodies were recovered from two of the five larynges but from none of ten larynges obtained from autopsy controls.

摘要

职业性接触石棉在流行病学上与喉癌有关；然而，尚未对喉内石棉小体进行查找或定量分析。本报告涉及一项尸检研究，该研究对5名有职业性石棉接触史且已证实患有石棉相关肺部疾病的患者进行了检查，对其喉部组织切片进行了组织学检查，并采用消化浓缩技术从剩余的喉部组织中分离并定量分析石棉小体。黏膜中未出现发育异常的上皮变化。在5个喉部中的2个发现了石棉小体，但在10个尸检对照的喉部中均未发现。