Fellenberg A J, Phillipou G, Seamark R F
Biomed Mass Spectrom. 1980 Feb;7(2):84-7. doi: 10.1002/bms.1200070209.
6-Hydroxymelatonin sulphate, a unique urinary metabolite of melatonin, has been measured in human subjects for the first time using a chromatography mass spectrometry and an isotope labelled internal standard. Urinary levels in both males and females were similar and ranged from 25-125 nmol 24 h-1. A significant nocturnal elevations of 6-hydroxymelatonin sulphate was also established in a male subject.
6-硫酸羟基褪黑素是褪黑素一种独特的尿液代谢物，首次在人体受试者中使用色谱质谱法和同位素标记内标进行了测量。男性和女性的尿液水平相似，范围为25 - 125 nmol 24 h⁻¹。在一名男性受试者中还发现6-硫酸羟基褪黑素在夜间有显著升高。
