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[急性出血后最初几天大鼠肝脏和肾脏中的能量代谢]

[Energy metabolism in the liver and kidneys of rats during the 1st few days after acute hemorrhage].

作者信息

Kazueva T V, Seleznev S A

出版信息

Biull Eksp Biol Med. 1980 Jul;89(7):30-2.

PMID:7407369
Abstract

A relative stability of the adenylate nucleotide system redox of liver and kidney cells was recorded in rats during the first day after acute hemorrhage (2.5% of body weight) in spite of a severe course of the posthemorrhagic period. Energy metabolism was examined in the state of the decompensation of circulation at a blood pressure of 35-45 mm Hg that progressively fell down after a short-term stabilization at the level of 40-60 mm Hg. Comparison of the results obtained with the reported data warrant conclusion that the magnitude of the critical arterial blood pressure at which the test parameters change lies between 40 and 50mm Hg and can vary in relation to a number of the conditions.

摘要

在急性失血(失血量为体重的2.5%)后的第一天,尽管出血后时期病情严重,但大鼠肝脏和肾脏细胞的腺苷酸核苷酸系统氧化还原仍呈现相对稳定性。在循环失代偿状态下,于血压35 - 45 mmHg时对能量代谢进行了检查,该血压在短暂稳定于40 - 60 mmHg水平后逐渐下降。将所得结果与已报道数据进行比较,可得出结论:测试参数发生变化时的临界动脉血压值在40至50 mmHg之间,且可能因多种条件而有所不同。

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