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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Gilbert A B, Hardie M A, Perry M M, Dick H R, Wells J W

Br Poult Sci. 1980 Jul;21(4):257-63. doi: 10.1080/00071668008416667.

The relationships between length, width and height of the maturing ovarian follicle of the domestic fowl (Gallus domesticus) are shown. 2. During the rapid-growth phase (yolk deposition) of the oocyte, i.e. an increase in size from about 9 mm diameter to 35 mm diameter, there is about a 15-fold increase in its surface area. During this time the number of granulosa cells adjacent to the oocyte increases by about 5-fold. 3. The granulosa cells become flatter during the growth period of the follicle, consequently increasing their surface area adjacent to the oocyte by about 3-fold. 4. Together the change in shape of the granulosa cells and the increase in their number account for the increase in area of the granulosa layer during follicular growth. 5. Measurement of the DNA content of the granulosa layer indicated a progressive decrease in the cellular content of DNA as the follicle matures.

展示了家鸡（原鸡）成熟卵泡的长度、宽度和高度之间的关系。2. 在卵母细胞的快速生长阶段（卵黄沉积），即直径从约9毫米增加到35毫米时，其表面积增加了约15倍。在此期间，与卵母细胞相邻的颗粒细胞数量增加了约5倍。3. 在卵泡生长期间，颗粒细胞变得更扁平，因此其与卵母细胞相邻的表面积增加了约3倍。4. 颗粒细胞形状的变化及其数量的增加共同导致了卵泡生长期间颗粒层面积的增加。5. 对颗粒层DNA含量的测量表明，随着卵泡成熟，细胞内DNA含量逐渐减少。

Gilbert A B, Hardie M A, Perry M M, Dick H R, Wells J W

Br Poult Sci. 1980 Jul;21(4):257-63. doi: 10.1080/00071668008416667.

The relationships between length, width and height of the maturing ovarian follicle of the domestic fowl (Gallus domesticus) are shown. 2. During the rapid-growth phase (yolk deposition) of the oocyte, i.e. an increase in size from about 9 mm diameter to 35 mm diameter, there is about a 15-fold increase in its surface area. During this time the number of granulosa cells adjacent to the oocyte increases by about 5-fold. 3. The granulosa cells become flatter during the growth period of the follicle, consequently increasing their surface area adjacent to the oocyte by about 3-fold. 4. Together the change in shape of the granulosa cells and the increase in their number account for the increase in area of the granulosa layer during follicular growth. 5. Measurement of the DNA content of the granulosa layer indicated a progressive decrease in the cellular content of DNA as the follicle matures.

展示了家鸡（原鸡）成熟卵泡的长度、宽度和高度之间的关系。2. 在卵母细胞的快速生长阶段（卵黄沉积），即直径从约9毫米增加到35毫米时，其表面积增加了约15倍。在此期间，与卵母细胞相邻的颗粒细胞数量增加了约5倍。3. 在卵泡生长期间，颗粒细胞变得更扁平，因此其与卵母细胞相邻的表面积增加了约3倍。4. 颗粒细胞形状的变化及其数量的增加共同导致了卵泡生长期间颗粒层面积的增加。5. 对颗粒层DNA含量的测量表明，随着卵泡成熟，细胞内DNA含量逐渐减少。