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幼鼠弯曲杆菌肠炎

Campylobacter enteritis in young mice.

作者信息

Madge D S

出版信息

Digestion. 1980;20(6):389-94. doi: 10.1159/000198479.

Abstract

Young mice aged 4--6 weeks and old mice aged 24--26 weeks were inoculated with standard, single, oral doses of two strains of human pathogenic 'related' campylobacters and in vitro small intestinal solute absorption and fluid transfer measured 7 days after inoculation. Young inoculated mice showed significantly lowered D-glucose and D-galactose absorption; in old inoculated mice absorption of these solutes remained unaltered. In young inoculated mice absorption of D-glucose was uniformly depressed in the distal four-fifths of the small intestine; absorption in the proximal one-fifth remained unaltered. Fluid transfer from the entire small intestine or segments of intestine remained unchanged 7 days after inoculation.

摘要

给4至6周龄的幼鼠和24至26周龄的老龄鼠口服标准单剂量的两种人类致病性“相关”弯曲杆菌菌株,接种7天后测量体外小肠溶质吸收和液体转运情况。接种的幼鼠D-葡萄糖和D-半乳糖吸收显著降低;接种的老龄鼠这些溶质的吸收未发生改变。接种的幼鼠小肠远端五分之四区域的D-葡萄糖吸收均受到抑制;近端五分之一区域的吸收未发生改变。接种7天后,整个小肠或肠段的液体转运未发生变化。

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