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幼鼠弯曲杆菌肠炎

Campylobacter enteritis in young mice.

作者信息

Madge D S

出版信息

Digestion. 1980;20(6):389-94. doi: 10.1159/000198479.

DOI:10.1159/000198479
PMID:7409349
Abstract

Young mice aged 4--6 weeks and old mice aged 24--26 weeks were inoculated with standard, single, oral doses of two strains of human pathogenic 'related' campylobacters and in vitro small intestinal solute absorption and fluid transfer measured 7 days after inoculation. Young inoculated mice showed significantly lowered D-glucose and D-galactose absorption; in old inoculated mice absorption of these solutes remained unaltered. In young inoculated mice absorption of D-glucose was uniformly depressed in the distal four-fifths of the small intestine; absorption in the proximal one-fifth remained unaltered. Fluid transfer from the entire small intestine or segments of intestine remained unchanged 7 days after inoculation.

摘要

给4至6周龄的幼鼠和24至26周龄的老龄鼠口服标准单剂量的两种人类致病性“相关”弯曲杆菌菌株,接种7天后测量体外小肠溶质吸收和液体转运情况。接种的幼鼠D-葡萄糖和D-半乳糖吸收显著降低;接种的老龄鼠这些溶质的吸收未发生改变。接种的幼鼠小肠远端五分之四区域的D-葡萄糖吸收均受到抑制;近端五分之一区域的吸收未发生改变。接种7天后,整个小肠或肠段的液体转运未发生变化。

相似文献

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Campylobacter enteritis in young mice.幼鼠弯曲杆菌肠炎
Digestion. 1980;20(6):389-94. doi: 10.1159/000198479.
2
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引用本文的文献

1
Intestinal colonization of neonatal animals by Campylobacter fetus subsp. jejuni.胎儿弯曲杆菌空肠亚种对新生动物的肠道定植
Infect Immun. 1981 Sep;33(3):884-92. doi: 10.1128/iai.33.3.884-892.1981.
2
Pathogenicity of Campylobacter jejuni isolates from animals and humans.来自动物和人类的空肠弯曲菌分离株的致病性。
Infect Immun. 1982 Oct;38(1):46-52. doi: 10.1128/iai.38.1.46-52.1982.
3
Culture supernatants of Campylobacter jejuni induce a secretory response in jejunal segments of adult rats.空肠弯曲菌的培养上清液可诱导成年大鼠空肠段产生分泌反应。
Infect Immun. 1983 Apr;40(1):429-31. doi: 10.1128/iai.40.1.429-431.1983.
4
Experimental Campylobacter jejuni infection of adult mice.成年小鼠的空肠弯曲菌实验性感染。
Infect Immun. 1983 Feb;39(2):908-16. doi: 10.1128/iai.39.2.908-916.1983.
5
Morphologic observations of experimental Campylobacter jejuni infection in the hamster intestinal tract.
Am J Pathol. 1986 Jan;122(1):152-9.
6
Colonization and infection of athymic and euthymic germfree mice by Campylobacter jejuni and Campylobacter fetus subsp. fetus.空肠弯曲菌和胎儿弯曲菌亚种对无胸腺和有胸腺无菌小鼠的定植与感染
Infect Immun. 1986 Aug;53(2):378-83. doi: 10.1128/iai.53.2.378-383.1986.