Blockey N J, Gibson A A, Goel K M
J Bone Joint Surg Br. 1980 Aug;62(3):368-71. doi: 10.1302/0301-620X.62B3.7410470.
Seven out of 22 children with monarticular juvenile rheumatoid arthritis (MJRA) developed involvement of other joints between six months and three and a half years from the onset. In the other 15 patients the disease has remained monarticular for between one and 16 years (mean six years). Chronic iridocyclitis was seen in three of the five boys, two with antinuclear antibodies. Children with MJRA and antinuclear antibodies should have periodic ophthalmic assessment. Synovial biopsy was of value primarily in excluding other cases of arthritis, but there was only limited correlation between the histological findings and the subsequent course of the disease.
22例单关节型幼年类风湿性关节炎（MJRA）患儿中，有7例在发病后6个月至3年半之间出现了其他关节受累。另外15例患者的疾病在1至16年（平均6年）内一直局限于单关节。5名男孩中有3名出现慢性虹膜睫状体炎，其中2名有抗核抗体。患有MJRA和抗核抗体的儿童应定期进行眼科评估。滑膜活检主要有助于排除其他关节炎病例，但组织学检查结果与疾病后续病程之间的相关性有限。
