大鼠垂体神经中间叶中胆碱乙酰转移酶活性的不均匀分布。

An uneven distribution of choline acetyltransferase activity in the pituiatry neurointermediate lobe of the rat.

作者信息

Gallardo M G, Cannata M A, Tramezzani J H

出版信息

J Endocrinol. 1980 Jun;85(3):497-501. doi: 10.1677/joe.0.0850497.

DOI:10.1677/joe.0.0850497

Abstract

The neurointermediate lobe of the pituitary gland of male rats was assayed for choline acetyltransferase (CAT) activity. Precise microsample punches were obtained from neurohypophysial tissue, pure pars intermedia tissue and from the junction area between them. The level of CAT activity (pmol/h per microgram protein) in the neurohypophysis, pars intermedia and junction area were 0.390 +/- 0.038 (S.E.M.), 0.228 +/- 0.042 and 1.824 +/- 0.268 respectively. These values show an uneven distribution of CAT in the neurointermediate lobe. The hypothesis of a cholinergic system located in the junction area has been advanced.

摘要

对雄性大鼠垂体神经中间叶进行了胆碱乙酰转移酶（CAT）活性测定。从神经垂体组织、纯粹的中间部组织以及它们之间的交界区域获取了精确的微量样本切片。神经垂体、中间部和交界区域的CAT活性水平（每微克蛋白质每小时的皮摩尔数）分别为0.390±0.038（标准误）、0.228±0.042和1.824±0.268。这些数值表明CAT在神经中间叶中的分布不均。关于位于交界区域的胆碱能系统的假说已经被提出。