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真菌性膀胱炎:认识、诊断与治疗

Fungal cystitis: awareness, diagnosis and treatment.

作者信息

Rohner T J, Tuliszewski R M

出版信息

J Urol. 1980 Jul;124(1):142-4. doi: 10.1016/s0022-5347(17)55334-3.

DOI:10.1016/s0022-5347(17)55334-3
PMID:7411704
Abstract

We report 4 cases of fungal cystitis. All patients had severe urgency, frequency and nocturia with sterile pyuria and microhematuria. Significant fungal growth was observed on routine blood agar cultur. Bladder biopsy was necessary to rule out tumor. Of the patients none responded to watchful waiting, 1 responded to intermittent daily bladder instillation of amphortericin B, 2 improved with oral 5-fluorocytosine, in addition to amphotericin B bladder instillations, and 1 required intravenous amphotericin B after unsuccessful response to 5-fluorocytosine and amphotericin B bladder treatments.

摘要

我们报告了4例真菌性膀胱炎病例。所有患者均有严重的尿急、尿频和夜尿症,伴有无菌性脓尿和镜下血尿。在常规血琼脂培养中观察到大量真菌生长。需要进行膀胱活检以排除肿瘤。所有患者中无人对观察等待有反应,1例患者对两性霉素B每日间歇性膀胱灌注有反应,2例患者除两性霉素B膀胱灌注外,口服5-氟胞嘧啶后病情改善,1例患者在对5-氟胞嘧啶和两性霉素B膀胱治疗无反应后需要静脉注射两性霉素B。

相似文献

1
Fungal cystitis: awareness, diagnosis and treatment.真菌性膀胱炎:认识、诊断与治疗
J Urol. 1980 Jul;124(1):142-4. doi: 10.1016/s0022-5347(17)55334-3.
2
Amphotericin B and flucytosine in the treatment of candidal cystitis.两性霉素B与氟胞嘧啶治疗念珠菌性膀胱炎
Clin Pharm. 1982 Jul-Aug;1(4):349-52.
3
Parenteral 5-fluorocytosine in the therapy of systemic mycoses.胃肠外给予5-氟胞嘧啶治疗全身性真菌病。
Ann N Y Acad Sci. 1988;544:571-4. doi: 10.1111/j.1749-6632.1988.tb40454.x.
4
Fungal infections in iatrogenically compromised hosts.医源性免疫功能受损宿主中的真菌感染。
Adv Intern Med. 1998;43:321-71.
5
Evaluation and treatment of urinary candidiasis.
South Med J. 1979 Dec;72(12):1578-81. doi: 10.1097/00007611-197912000-00025.
6
Combined treatment with amphotericin B and flucytosine in severe fungal infections.两性霉素B与氟胞嘧啶联合治疗严重真菌感染。
J Antimicrob Chemother. 1976 Sep;2(3):239-46. doi: 10.1093/jac/2.3.239.
7
Candidal cystitis. Management by continuous bladder irrigation with amphotericin B.念珠菌性膀胱炎。两性霉素B持续膀胱冲洗治疗
JAMA. 1973 Jun 18;224(12):1636-7. doi: 10.1001/jama.224.12.1636.
8
Amphotericin B lavage in the treatment of Candidial cystitis.两性霉素B灌洗治疗念珠菌性膀胱炎。
Br J Urol. 1972 Aug;44(4):475-80. doi: 10.1111/j.1464-410x.1972.tb10109.x.
9
Antifungal agents used for deep-seated mycotic infections.
Mayo Clin Proc. 1983 Apr;58(4):223-31.
10
Pharmacokinetics, outcome of treatment, and toxic effects of amphotericin B and 5-fluorocytosine in neonates.
J Pediatr. 1990 May;116(5):791-7. doi: 10.1016/s0022-3476(05)82674-5.

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Fungal urinary tract infections in the elderly: treatment guidelines.老年人真菌性尿路感染:治疗指南
Drugs Aging. 1996 Feb;8(2):89-96. doi: 10.2165/00002512-199608020-00003.