Rohner T J, Tuliszewski R M
J Urol. 1980 Jul;124(1):142-4. doi: 10.1016/s0022-5347(17)55334-3.
We report 4 cases of fungal cystitis. All patients had severe urgency, frequency and nocturia with sterile pyuria and microhematuria. Significant fungal growth was observed on routine blood agar cultur. Bladder biopsy was necessary to rule out tumor. Of the patients none responded to watchful waiting, 1 responded to intermittent daily bladder instillation of amphortericin B, 2 improved with oral 5-fluorocytosine, in addition to amphotericin B bladder instillations, and 1 required intravenous amphotericin B after unsuccessful response to 5-fluorocytosine and amphotericin B bladder treatments.
我们报告了4例真菌性膀胱炎病例。所有患者均有严重的尿急、尿频和夜尿症,伴有无菌性脓尿和镜下血尿。在常规血琼脂培养中观察到大量真菌生长。需要进行膀胱活检以排除肿瘤。所有患者中无人对观察等待有反应,1例患者对两性霉素B每日间歇性膀胱灌注有反应,2例患者除两性霉素B膀胱灌注外,口服5-氟胞嘧啶后病情改善,1例患者在对5-氟胞嘧啶和两性霉素B膀胱治疗无反应后需要静脉注射两性霉素B。