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感染绵羊肺腺瘤病(jaagsiekte)的绵羊肺细胞DNA中存在绵羊疱疹病毒DNA序列。

Presence of Herpesvirus ovis DNA sequences in cellular DNA from sheep lungs affected with jaagsiekte (pulmonary adenomatosis).

作者信息

De Villiers E M, Verwoerd D W

出版信息

Onderstepoort J Vet Res. 1980 Jun;47(2):109-12.

PMID:7413161
Abstract

To investigate further the possible involvement of Herpesvirus ovis in the aetiology of jaagsiekte, the kinetics of reassociation of viral DNA and DNA isolated from tumour tissue as well as from cell cultures derived from it were studied. Although DNA-DNA hybridization could be demonstrated in 2 cases of jaagsiekte, no correlation was found between the presence of Herpesvirus ovis genome sequences and the occurrence of the disease.

摘要

为了进一步研究绵羊疱疹病毒在绵羊肺腺瘤病因学中可能的作用,对病毒DNA与从肿瘤组织以及由肿瘤组织衍生的细胞培养物中分离的DNA的重新结合动力学进行了研究。虽然在2例绵羊肺腺瘤病例中可证实DNA-DNA杂交,但未发现绵羊疱疹病毒基因组序列的存在与该病的发生之间存在相关性。

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