Toivonen H
Res Commun Chem Pathol Pharmacol. 1980 Aug;29(2):243-9.
One day after a single exposure of rats to cigarette smoke their blood pressure responses to intravenous injections of angiotensin I and II were slightly increased in comparison to sham-exposed animals. When the exposure was repeated daily during ten consecutive days, no changes could be detected. These results suggest, that the total conversion of angiotensin I in vivo was not affected by cigarette smoke but the sensitivity of rats to angiotensin II was slightly increased after a single exposure to cigarette smoke.
大鼠单次暴露于香烟烟雾一天后，与假暴露动物相比，它们对静脉注射血管紧张素I和II的血压反应略有增加。当连续十天每天重复暴露时，则未检测到变化。这些结果表明，香烟烟雾不影响血管紧张素I在体内的总转化率，但大鼠单次暴露于香烟烟雾后对血管紧张素II的敏感性略有增加。
