Yü T, Talbott J H
Semin Arthritis Rheum. 1980 Aug;10(1):1-9. doi: 10.1016/0049-0172(80)90010-4.
Patients with primary gout live as long as the nongouty male in the general population. Coronary heart disease is the leading cause of death in the gouty and nongouty population. There is a parallel decline in mortality particularly from coronary heart disease as that in the general population. This phenomenon is related to a number of specific and nonspecific factors. The changes in life styles and major risk factors may be counted as important influences. It is also clear that the impact of the disturbance of uric acid metabolism has not placed a particular individual in a category with any significantly inherent greater risk from intimately or remotely related causes of morbidity or mortality.
原发性痛风患者的寿命与普通人群中的非痛风男性一样长。冠心病是痛风患者和非痛风人群的主要死因。痛风患者的死亡率,尤其是冠心病导致的死亡率,与普通人群呈平行下降趋势。这种现象与一些特定和非特定因素有关。生活方式的改变和主要危险因素可能是重要影响因素。同样明显的是,尿酸代谢紊乱的影响并未使特定个体因直接或间接相关的发病或死亡原因而面临任何显著更高的固有风险。