Shul'ga N I
Vopr Onkol. 1980;26(8):32-5.
Catecholamines and cortisol in blood were studied in 91 lung cancer patients and in 11 patients with benign neoplasms in the lung. The investigation peformed has shown a certain dependence between the process stage and the sympatho-adrenal system functioning. Total amount of catecholamines is increased as the disease progresses, reaching the maximum at stage III and is sharply decreased at stage IV. A correlation between adrenaline and noradrenaline is changed in favour of a relative predominance of the adrenal link in the sympatho-adrenal system. The cortisol level during the malignant tumor growth is changed in an undular fashion and is mostly raised in patients with stage I and II. The development of metastases is associated with some tendency toward raising catecholamines level and lowering the functional activity of the adrenal cortex.
对91例肺癌患者和11例肺部良性肿瘤患者的血液中的儿茶酚胺和皮质醇进行了研究。所进行的调查显示，病程阶段与交感-肾上腺系统功能之间存在一定的相关性。随着疾病进展，儿茶酚胺总量增加，在III期达到最高值，而在IV期急剧下降。肾上腺素与去甲肾上腺素之间的相关性发生变化，有利于交感-肾上腺系统中肾上腺环节的相对占优势。在恶性肿瘤生长过程中，皮质醇水平呈波浪式变化，在I期和II期患者中大多升高。转移的发生与儿茶酚胺水平升高和肾上腺皮质功能活性降低的某种趋势相关。
