Akhtar M, Valencia M, Thomas A M
Urology. 1978 Dec;12(6):721-4. doi: 10.1016/0090-4295(78)90443-0.
A fifty-four-year-old white woman with a history of episodic gross hematuria was diagnosed as having solitary primary amyloidosis of the urinary bladder involving a large segment of the dome and anterior wall. A segmental resection of the bladder was performed with good results. Electron microscopic examination of the lesion revealed evidence to indicate that amyloid in this case was produced by the fibroblasts within the lamina propria of the bladder. The mode of amyloidogenesis is identical to that noted in some of the previously published electron microscopic studies on localized amyloidosis of skin. Solitary primary amyloidosis of the urinary bladder is a rare lesion with only 46 cases having been previously reported in the literature.
一名54岁有发作性肉眼血尿病史的白人女性被诊断为膀胱孤立性原发性淀粉样变性，累及膀胱顶部和前壁的大部分。行膀胱部分切除术，效果良好。对病变进行电子显微镜检查发现有证据表明，本例中的淀粉样物质是由膀胱固有层内的成纤维细胞产生的。淀粉样变性的发生方式与之前一些关于皮肤局限性淀粉样变性的电子显微镜研究所指出的相同。膀胱孤立性原发性淀粉样变性是一种罕见病变，此前文献中仅报道过46例。
