Brückner B
Zentralbl Chir. 1980;105(6):366-70.
Bile acids and their metabolism play an important role in the pathogenesis of many gastro-intestinal diseases such as gallstone formation, biliary fistula, intestinal congestive symptoms, defective function of the terminal ileum, ulcer pathogenesis. The diagnostics has been improved by enzymatic estimation methods of the bile acids in the serum, functional tests and radioactive marking of the bile acids. Principles of causal surgical therapy as well as internal treatment can be derived from this new pathophysiological knowledge.
胆汁酸及其代谢在许多胃肠道疾病的发病机制中起着重要作用,如胆结石形成、胆瘘、肠道充血症状、回肠末端功能缺陷、溃疡发病机制。血清中胆汁酸的酶促测定方法、功能测试和胆汁酸的放射性标记改善了诊断。基于这一新的病理生理学知识,可以得出病因性手术治疗以及内科治疗的原则。