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[神经致敏大鼠后代大脑皮质中全神经胶质细胞和神经元周围神经胶质细胞数量变化的动态]

[Dynamics of quantitative shifts in total and perineuronal glia in the cerebral cortex of the progeny of neurosensitized rats].

作者信息

Konokotina G F

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1980;80(7):1068-71.

PMID:7415725
Abstract

The amount of general and perineuronal glia in the V layer of the sensomotor cortical area was studied during different stages /14-100 days/ of the postnatal period in the progeny born to previously neurosensitized rats. The study demonstrated a decrease in the amount of general glia in the early postnatal period, as well as a drop in amount of perineuronal satellites of large/especially small cells/during all the periods after birth. There was a higher rate in the increase of cortical glial cells in the newborn rats under test. It is assumed that the retardation following stimulation of the process of proliferation migration of glioblasts in the cortex is due to the influence of the neuroautoimmune conflict between the mother and fetus in the antenatal period.

摘要

在出生后不同阶段(14 - 100天),对先前经神经致敏的大鼠所产后代的感觉运动皮质区V层中的一般神经胶质细胞和神经元周围神经胶质细胞数量进行了研究。研究表明,出生后早期一般神经胶质细胞数量减少,并且在出生后的所有时期,大细胞(尤其是小细胞)的神经元周围卫星细胞数量均有所下降。受试新生大鼠的皮质神经胶质细胞增加速率更高。据推测,产前母胎之间的神经自身免疫冲突影响导致皮质中胶质母细胞增殖迁移过程受刺激后出现迟缓。

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