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实验室小鼠急性暴露于氧化锰。

Acute exposure of laboratory mice to manganese oxide.

作者信息

Adkins B, Luginbuhl G H, Gardner D E

出版信息

Am Ind Hyg Assoc J. 1980 Jul;41(7):494-500. doi: 10.1080/15298668091425130.

DOI:10.1080/15298668091425130
PMID:7415970
Abstract

An acute inhalation exposure of laboratory mice to respirable Mn3O4 aerosols is described. The generation system consisted of a Wright dust generator which produced 1.40 micrometer aerosols. A non-linear loss of deposited manganese from mouse lungs over the inital 24-hour post-exposure period was observed. Systemic distribution of the manganese was observed in various tissues following exposure.

摘要

描述了实验室小鼠急性吸入可吸入性四氧化三锰气溶胶的情况。生成系统由产生1.40微米气溶胶的赖特粉尘发生器组成。在暴露后的最初24小时内,观察到小鼠肺部沉积锰的非线性损失。暴露后在各种组织中观察到锰的全身分布。

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