Snyder S
Am J Gastroenterol. 1980 Apr;73(4):336-40.
The management of an agitated schizophrenic was complicated by the onset of severe hepatocellular dysfunction concomitant with the administration of fluphenazine, a drug which has rarely been implicated in phenothiazine jaundice. Since neuroleptics did lead to a dramatic improvement, the patient was treated with an antipsychotic from an alternative drug class. The differential diagnosis, approach to management and natural history are presented, along with a brief review of phenothiazine jaundice, with special emphasis on fluphenazine.
一名躁动的精神分裂症患者的治疗因在使用氟奋乃静时并发严重肝细胞功能障碍而变得复杂，氟奋乃静这种药物很少与吩噻嗪类黄疸有关。由于抗精神病药物确实使病情有显著改善，因此该患者接受了另一类替代药物的抗精神病治疗。文中介绍了鉴别诊断、治疗方法和自然病程，同时简要回顾了吩噻嗪类黄疸，特别强调了氟奋乃静。
