[Importance of the diagnosis of congenital developmental defects in the practice of pathologists].

Composite studies of 1286 stillborns and infants with congenital malformations (CMF) dying at the age under 1 year conducted in the Teratological Center of Minsk showed that in specialized therapeutic institutions the causes of CMF could be established in at least 70% of the cases. In the infant autopsy materials, 12% of CMF were associated with chromosome pathology, 17% with single gene mutations, over 40% had multifactor determinants and 2.7% were due to teratogenic effects.