Sandok B A, von Estorff I, Giuliani E R
Arch Neurol. 1980 Aug;37(8):485-8. doi: 10.1001/archneur.1980.00500570033004.
The records of 40 patients with pathologically verified atrial myxoma identified during the period 1957 to 1977 were studied. The patients ranged in age from 17 to 77 years; women predominated by a ratio of 3:1. Thirty-five patients had left atrial myxoma, three patients had right atrial myxoma, one patient had bilateral myxomas, and one patient had a right atrial myxoma and subsequent removal of a left atrial myxoma. Ten of the 37 patients (27%) with left atrial myxoma had at least one neurologic event suggesting ischemia secondary to embolization. Transient or permanent ischemic events were noted in the cerebral hemispheres, brainstem, cerebellum, retina, and spinal cord. Although some patients were seen at the initial evaluation with primarily neurologic events, cardiac and constitutional symptoms dominated the clinical picture. Echocardiography and sector scanning provide a practical method for early clinical diagnosis.
对1957年至1977年期间病理确诊为心房黏液瘤的40例患者的记录进行了研究。患者年龄在17岁至77岁之间；女性占主导，男女比例为3:1。35例患者患有左心房黏液瘤，3例患者患有右心房黏液瘤，1例患者患有双侧黏液瘤，1例患者患有右心房黏液瘤，随后又切除了左心房黏液瘤。37例左心房黏液瘤患者中有10例（27%）至少发生过一次提示栓塞继发缺血的神经系统事件。在大脑半球、脑干、小脑、视网膜和脊髓均发现了短暂性或永久性缺血事件。尽管有些患者在初次评估时主要表现为神经系统事件，但心脏和全身症状在临床表现中占主导地位。超声心动图和扇形扫描为早期临床诊断提供了一种实用方法。
