Arshavsky Y I, Orlovsky G N, Pavlova G A, Perret C
Brain Res. 1980 Nov 3;200(2):249-58. doi: 10.1016/0006-8993(80)90917-8.
The activity of neurons of the interpositus and lateral cerebellar nuclei was recorded during fictitious scratch reflex in thalamic cats immobilized with Flaxedil. Interpositus neurons were identified by antidromic response to stimulation of the contralateral red nucleus. The interpositus neurons responding to passive movements of the ipsilateral hindlimb manifested rhythmical modulation of the discharge in relation with the scratch cycle. The neurons generated bursts of impulses separated by periods of silence. Different neurons were active in different parts of the scratch cycle, but most of them were active in the second half of the flexor phase. When the scratch reflex was evoked on the contralateral side, rhythmical modulation was observed in about half of the neurons, and it was less pronounced than in the case of ipsilateral scratching. Rhythmical modulation of cerebellar neurons during fictitious scratching is determined by signals coming from the central spinal mechanism, generating rhythmical oscillations, via the ventral spinocerebellar tract (VSCT) and the spinoreticulocerebellar pathway (SRCP). Results of separate transections of these pathways showed that the VSCT plays the crucial role in modulating interpositus neurons. Neurons of the lateral nucleus exhibited no modulation during fictitious scratching.
在使用三碘季铵酚麻痹的丘脑猫进行虚拟搔抓反射期间，记录了间位核和小脑外侧核神经元的活动。通过对刺激对侧红核的逆向反应来识别间位核神经元。对同侧后肢被动运动有反应的间位核神经元，其放电表现出与搔抓周期相关的节律性调制。这些神经元产生由静息期分隔的冲动爆发。不同的神经元在搔抓周期的不同阶段活跃，但大多数在屈肌期的后半段活跃。当在对侧诱发搔抓反射时，约一半的神经元观察到节律性调制，且比同侧搔抓时不明显。虚拟搔抓期间小脑神经元的节律性调制由来自中枢脊髓机制的信号决定，这些信号通过腹侧脊髓小脑束（VSCT）和脊髓网状小脑通路（SRCP）产生节律性振荡。这些通路单独横断的结果表明，VSCT在调制间位核神经元中起关键作用。在虚拟搔抓期间，外侧核的神经元未表现出调制。
