von Holst T, Runnebaum B
Geburtshilfe Frauenheilkd. 1980 Sep;40(9):804-12.
After examination of ovarian and tubal function 246 women underwent 1238 AIH in 847 menstrual cycles. During the treatment period 74 patients became pregnant once or several times; altogether 99 pregnancies were observed. Whereas only 22 pregnancies occurred in cycles with AIH, the other 77 occurred in cycles without AIH. The ratio of pregnancies after AIH and those occurring without insemination decreases in relation to the degree of deterioration of the semen quality. With normal semen the ratio of pregnancies with AIH and those without AIH was 1:2.5. With semen of grade I this ratio became 1:4 and with grade II 1:10. On the basis of these results the following conclusions can be drawn: (1) with more or less normal semen quality and disturbance of the cervical mucus penetration AIH appeared to be reasonable; (2) with severe or even moderate subfertile semen findings AIH is not indicated; (3) an indication for AIH is the impossibility of cohabitation or ejaculation.
在对246名女性的卵巢和输卵管功能进行检查后,她们在847个月经周期中接受了1238次夫精人工授精(AIH)。在治疗期间,74名患者怀孕一次或多次;共观察到99次妊娠。其中,仅22次妊娠发生在进行AIH的周期,另外77次发生在未进行AIH的周期。与精液质量恶化程度相关,AIH后妊娠与未进行授精时妊娠的比例下降。精液正常时,AIH妊娠与未进行AIH妊娠的比例为1:2.5。精液为I级时,该比例变为1:4,II级时为1:10。基于这些结果,可以得出以下结论:(1)精液质量或多或少正常但宫颈黏液穿透存在障碍时,AIH似乎是合理的;(2)精液严重或中度亚生育时,不建议进行AIH;(3)AIH的指征是无法同居或射精。