Toniolo A, Matteucci D, Pistillo M P, Gori Z, Bendinelli M
J Gen Virol. 1980 Jul;49(1):203-8. doi: 10.1099/0022-1317-49-1-203.
The ability of spleen macrophages to support Friend leukaemia virus replication was studied by testing for infectivity in adherent cells obtained from mice at various times after infection. Virus-releasing macrophages appeared early after infection and reached a high proportion. The released virus was probably synthesized de novo since macrophage infectivity was strongly reduced by treatments which affected cellular viability or synthetic activities and electron microscopy showed C-type particles budding from macrophages.
通过检测感染后不同时间从小鼠获得的贴壁细胞的感染性，研究了脾巨噬细胞支持弗氏白血病病毒复制的能力。感染后早期出现了释放病毒的巨噬细胞，且比例很高。释放的病毒可能是重新合成的，因为影响细胞活力或合成活性的处理会大大降低巨噬细胞的感染性，并且电子显微镜显示有C型颗粒从巨噬细胞中出芽。
