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闭眼诱发癫痫发作:发生率及识别

Self-induction of epileptic seizures by eyeclosure: incidence and recognition.

作者信息

Binnie C D, Darby C E, De Korte R A, Wilkins A J

出版信息

J Neurol Neurosurg Psychiatry. 1980 May;43(5):386-9. doi: 10.1136/jnnp.43.5.386.

DOI:10.1136/jnnp.43.5.386
PMID:7420087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC490563/
Abstract

Self-induction of epileptic seizures is generally regarded as a rarity, chiefly observed in patients of subnormal intelligence. During EEG recordings with open eyes in a consecutive series of 48 photosensitive patients, however, 13 subjects induced paroxysmal activity of seizures by eyeclosure with forced upward deviation of the eyes. Eyeclosure on command produced a different type of oculographic artefact and induced paroxysmal activity in only one subject. Two patients were of subnormal intelligence but all displayed psychiatric or psychosocial problems. The incidence of induced paroxysmal activity was reduced by reduction of ambient lighting. Eight patients admitted self-induction of seizures. We conclude that this phenomenon occurs more often than was previously supposed and can be recongnized by the recording in photosensitive patients of prolonged EEGs with eyes open and in a brightly lit environment.

摘要

癫痫发作的自我诱导通常被认为是罕见的,主要见于智力低于正常水平的患者。然而,在对48例连续的光敏患者进行睁眼脑电图记录期间,有13名受试者通过闭眼并强迫眼球向上偏转而诱发了癫痫发作的阵发性活动。按指令闭眼产生了不同类型的眼动图伪迹,仅在一名受试者中诱发了阵发性活动。两名患者智力低于正常水平,但均表现出精神或社会心理问题。减少环境光照可降低诱发阵发性活动的发生率。8名患者承认有自我诱导癫痫发作的情况。我们得出结论,这种现象比以前认为的更常发生,并且可以通过在明亮环境中对光敏患者进行长时间睁眼脑电图记录来识别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a87f/490563/562caf72d20b/jnnpsyc00073-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a87f/490563/562caf72d20b/jnnpsyc00073-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a87f/490563/562caf72d20b/jnnpsyc00073-0019-a.jpg

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引用本文的文献

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Ecstatic Epileptic Seizures: A Glimpse into the Multiple Roles of the Insula.狂喜性癫痫发作:窥探脑岛的多重作用
Front Behav Neurosci. 2016 Feb 17;10:21. doi: 10.3389/fnbeh.2016.00021. eCollection 2016.
2
Mental imagery of photic stimulation provokes paroxysmal EEG activity in a photosensitive patient who self-induces seizures.
Ital J Neurol Sci. 1997 Apr;18(2):93-100. doi: 10.1007/BF01999569.
3
Eyelid myoclonia with typical absences: an epilepsy syndrome.伴典型失神发作的眼睑肌阵挛:一种癫痫综合征。

本文引用的文献

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