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经枕大池注射高岭土后犬实验性交通性脊髓空洞症。第2部分。压力研究。

Experimental communicating syringomyelia in dogs after cisternal kaolin injection. Part 2. Pressure studies.

作者信息

Williams B

出版信息

J Neurol Sci. 1980 Oct;48(1):109-22. doi: 10.1016/0022-510x(80)90154-9.

Abstract

Pressure measurements in cerebrospinal fluid have been made from the ventricles and the spinal subarachnoid space in dogs made hydrocephalic by intracisternal injections of kaolin. Raised intraventricular pressure has been confirmed in the confirmed in the ventricles. The spinal pressure is usually markedly different from that in the head, confirming that the arachnoiditis produced around the cistern isolates the spinal subarachnoid space from the CSF in the head. Pulsatile pressures have been investigated specifically and the interrelationship between the pulsation and baseline pressures in the development of communicating syringomyelia discussed. There are differences between these experimental animals and the human disease, particularly in the baseline pressures which are usually equal in the head and the spine of humans at rest even in cases with syringomyelia.

摘要

通过向犬的脑池内注射高岭土制造脑积水模型,对其脑室和脊髓蛛网膜下腔的脑脊液压力进行了测量。已证实脑室内压力升高。脊髓压力通常与头部压力明显不同,这证实了脑池周围产生的蛛网膜炎将脊髓蛛网膜下腔与颅内脑脊液分隔开来。已专门研究了搏动性压力,并讨论了交通性脊髓空洞症发展过程中搏动压力与基线压力之间的相互关系。这些实验动物与人类疾病存在差异,特别是在基线压力方面,即使在患有脊髓空洞症的情况下,人类静止时头部和脊柱的基线压力通常也是相等的。

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