Holmes G L, Sackellares J C, McKiernan J, Ragland M, Dreifuss F E
J Pediatr. 1980 Oct;97(4):554-8. doi: 10.1016/s0022-3476(80)80008-4.
Pseudoseizures, clinical events that superficially resemble epileptic attacks but which are not associated with central nervous system paroxysmal activity, are often difficult to differentiate from epileptic seizures. To evaluate the frequency and clinical manifestations of pseudoseizures in children with intractable seizures, children admitted to a Comprehensive Epilepsy Unit received prolonged simultaneous EEG telemetry and video recording. Pseudoseizures occurred in 11 of 53 pediatric patients admitted during the study period. Eight of the 11 patients with pseudoseizures also had documented epileptic seizures. Clinical characteristics of pseudoseizures and epileptic seizures documented by TEEG-VR were compared. Degree and duration of the postictal state, incontinence, combativeness, relationship to stress, and response to anticonvulsant medication were useful differentiating criteria. Pseudoseizures are not unusual in pediatric patients, often occur concurrently with epileptic seizures, and may be difficult to diagnose. However, careful clinical observation may offer clues in differentiating pseudoseizures from epileptic seizures.
假性发作是一种临床表现，表面上类似于癫痫发作，但与中枢神经系统阵发性活动无关，通常很难与癫痫发作区分开来。为了评估难治性癫痫患儿假性发作的频率和临床表现，入住综合癫痫病房的患儿接受了长时间同步脑电图遥测和视频记录。在研究期间收治的53例儿科患者中，有11例出现了假性发作。11例假性发作患者中有8例也记录有癫痫发作。比较了通过电视脑电图-视频记录（TEEG-VR）记录的假性发作和癫痫发作的临床特征。发作后状态的程度和持续时间、大小便失禁、好斗性、与压力的关系以及对抗惊厥药物的反应是有用的鉴别标准。假性发作在儿科患者中并不罕见，常与癫痫发作同时发生，且可能难以诊断。然而，仔细的临床观察可能会为区分假性发作和癫痫发作提供线索。
