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慢性失代偿性重症肌无力罕见的心肺并发症。

Rare cardiopulmonary complications of chronically decompensated myasthenia gravis.

作者信息

Chisholm J C, Gilson A

出版信息

J Natl Med Assoc. 1980 Oct;72(10):997-8.

PMID:7420443
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2552523/
Abstract

Although myasthenia gravis (MG) is frequently mentioned in standard textbooks and journal articles as a rare cause for pulmonary hypertension and right heart failure, no case can actually be found in the literature. The case described in this report is the first documented case of chronically decompensated MG manifesting itself as pulmonary hypertension, severe right heart failure, and functional prolapse of both the mitral and tricuspid valves. Interestingly, no hepatic biochemical abnormalities were present in spite of significant congestive hepatomegaly.

摘要

尽管重症肌无力(MG)在标准教科书和期刊文章中经常被提及是肺动脉高压和右心衰竭的罕见病因,但实际上在文献中找不到相关病例。本报告中描述的病例是首例有记录的慢性失代偿性重症肌无力病例,表现为肺动脉高压、严重右心衰竭以及二尖瓣和三尖瓣功能性脱垂。有趣的是,尽管存在明显的充血性肝肿大,但未出现肝脏生化异常。

相似文献

1
Rare cardiopulmonary complications of chronically decompensated myasthenia gravis.慢性失代偿性重症肌无力罕见的心肺并发症。
J Natl Med Assoc. 1980 Oct;72(10):997-8.
2
Reversible pulmonary hypertension and isolated right-sided heart failure associated with hyperthyroidism.与甲状腺功能亢进相关的可逆性肺动脉高压和孤立性右心衰竭。
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Cardiol Rev. 2004 Nov-Dec;12(6):299-305. doi: 10.1097/01.crd.0000137259.83169.e3.
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Aspects of mitral and tricuspid regurgitation.二尖瓣和三尖瓣反流的相关方面。
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Tricuspid regurgitation in patients with acquired, chronic, pure mitral regurgitation. I. Prevalence, diagnosis, and comparison of preoperative clinical and hemodynamic features in patients with and without tricuspid regurgitation.获得性慢性单纯二尖瓣反流患者的三尖瓣反流。I. 有和无三尖瓣反流患者术前临床和血流动力学特征的患病率、诊断及比较
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[Postoperative behavior of pulmonary artery pressure and right ventricular remodeling following orthotopic heart transplantation].[原位心脏移植术后肺动脉压力及右心室重构的行为]
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Idiopathic annular dilation: a rare cause of isolated severe tricuspid regurgitation.特发性环状扩张:孤立性严重三尖瓣反流的罕见原因。
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本文引用的文献

1
A hospital study of congestive heart failure, with special reference to cor pulmonale.一项关于充血性心力衰竭的医院研究,特别提及肺源性心脏病。
Br Med J. 1959 Aug 22;2(5146):201-8. doi: 10.1136/bmj.2.5146.201.
2
The present status of the treatment of cor pulmonale.肺心病的治疗现状
N Y State J Med. 1957 Jan 1;57(1):74-82.
3
Reversible respiratory paralysis associated with polymyxin therapy.与多粘菌素治疗相关的可逆性呼吸麻痹。
Ann Intern Med. 1968 Feb;68(2):318-27. doi: 10.7326/0003-4819-68-2-318.
4
The mitral valve prolapse syndrome. Spectrum and therapy.二尖瓣脱垂综合征。范围与治疗。
Med Clin North Am. 1979 Mar;63(2):337-53. doi: 10.1016/s0025-7125(16)31700-x.