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顽固性间质性膀胱炎的外科治疗

The surgical treatment of intractable interstitial cystitis.

作者信息

Freiha F S, Faysal M H, Stamey T A

出版信息

J Urol. 1980 May;123(5):632-4. doi: 10.1016/s0022-5347(17)56070-x.

Abstract

Nineteen patients with severe intractable interstitial cystitis were treated surgically with either cecocystoplasty, urinary diversion with or without cystectomy, cystolysis or segmental bladder resection. Of the 6 patients who underwent an augmentation cecocystoplasty 4 were cured and 2 ultimately had urinary diversion before cure. Of the 7 patients who underwent urinary diversion with or without total cystectomy 6 were cured. In the cystolysis group the suprapubic pain was relieved either totally or partially in all 5 cases, and nocturia and urinary frequency were reduced substantially in each. However, only 1 patient was cured completely of all symptoms. The patient who underwent segmental resection of the bladder experienced only temporary symptomatic relief. Postoperative complications included pyocystis in 2 patients who had urinary diversion without cystectomy and hydroureteronephrosis in 1 patient after ureterosigmoidostomy that required multiple procedures. The place for each of these major surgical procedures in the treatment of intractable interstitial cystitis is discussed.

摘要

19例重度难治性间质性膀胱炎患者接受了手术治疗,手术方式包括盲肠膀胱扩大术、有或无膀胱切除术的尿流改道术、膀胱松解术或膀胱部分切除术。在接受盲肠膀胱扩大术的6例患者中,4例治愈,2例在治愈前最终接受了尿流改道术。在接受有或无全膀胱切除术的尿流改道术的7例患者中,6例治愈。在膀胱松解术组中,所有5例患者的耻骨上疼痛均得到完全或部分缓解,夜尿症和尿频均显著减少。然而,只有1例患者所有症状完全治愈。接受膀胱部分切除术的患者仅获得了症状的暂时缓解。术后并发症包括2例未行膀胱切除术而行尿流改道术的患者发生膀胱积脓,1例输尿管乙状结肠吻合术后发生输尿管肾积水,需要多次手术治疗。本文讨论了这些主要外科手术在难治性间质性膀胱炎治疗中的地位。

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