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[高血压早期发病机制的脑部相关问题]

[Cerebral aspects of the pathogenesis of the early stages of hypertension].

作者信息

Veĭn A M, Alekseev V V, Golubev V L

出版信息

Kardiologiia. 1980 Sep;20(9):34-8.

PMID:7420844
Abstract

The functional condition of the various links of the nonspecific cerebral systems and their role in the pathogenesis of the early stages of hypertensive disease were studied. The results showed that such patients have anxiety-neurotic disorders and sympathetic shifts in the circulatory system. Emotional stress leads to elevation of arterial pressure and prolongation of the initally increased delta-sleep in the structure of night sleep. Analysis of the results disclosed two main psychophysiological types of reaction to emotional stress in patients with hypertensive disease. Elevation of arterial pressure at the expense of the stroke volume is attended by prolongation of the stage of quick sleep on the following night and prolongation of delta-sleep because of peripheral vascular resistance. These types are distinguished according to the psychological characteristics.

摘要

研究了非特异性脑系统各环节的功能状态及其在高血压病早期发病机制中的作用。结果表明,此类患者存在焦虑神经症性障碍以及循环系统的交感神经变化。情绪应激会导致动脉血压升高以及夜间睡眠结构中最初增加的δ睡眠延长。对结果的分析揭示了高血压病患者对情绪应激反应的两种主要心理生理类型。以每搏输出量为代价导致的动脉血压升高,伴随着次晚快速睡眠阶段的延长以及由于外周血管阻力导致的δ睡眠延长。这些类型根据心理特征加以区分。

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