Prediction of response to antihypertensive therapy with prazosin.
作者信息
MacCarthy E P, Frost G W, Monaghan J C, Mennie B A, Stokes G S
出版信息
Med J Aust. 1980 Jul 26;2(SP1):12-4.
PMID:7421719
Abstract
Blood-pressure responses and changes in plasma drug concentration were studied in 11 hypertensive patients after an initial oral dose of 2 mg of prazosin. Subsequently, blood pressure was monitored during long-term treatment with prazosin. The prazosin reactivity index, a value derived during the first-dose study, appeared to predict the long-term antihypertensive effect of prazosin alone or prazosin combined with bendrofluazide.
摘要
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