Horváth T, Nagy I, Gógl A
Acta Med Acad Sci Hung. 1978;35(2):105-13.
The relationship between steroid cholestasis and antithrombin-III activity were examined in users of oral contraceptives (Infecundin or Bisecurin) and in patients receiving anabolic hormone therapy (Nerobol). The control group for the oral contraceptive users consisted of patients with spontaneous anovulation. The untreated control group consisted of healthy women in the reproductive age. The increase in antithrombin-III activity was found to be directly related to the decline of anion excretion. Latent cholestasis in itself is not associated with an increased antithrombin-III activity, nor is the activity of antithrombin-III affected by long-continued use of those anabolic steroids which produce no decrease in anion excretion.
对口服避孕药（Infecundin或Bisecurin）使用者以及接受同化激素治疗（Nerobol）的患者，研究了类固醇性胆汁淤积与抗凝血酶III活性之间的关系。口服避孕药使用者的对照组为自然无排卵患者。未治疗的对照组为育龄期健康女性。发现抗凝血酶III活性的增加与阴离子排泄的减少直接相关。潜在的胆汁淤积本身与抗凝血酶III活性增加无关，且抗凝血酶III的活性也不受长期使用那些不会导致阴离子排泄减少的同化类固醇的影响。
