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不育男性克罗米芬治疗期间血清和精浆中的类固醇水平。

Steroid levels in the serum and seminal plasma during clomiphene therapy in hypofertile men.

作者信息

Sas M, Falkay G, Szöllósi J

出版信息

Acta Med Acad Sci Hung. 1978;35(2):159-65.

PMID:742340
Abstract

The serum and seminal plasma concentrations of androstenedione, testosterone, dihydrotestosterone and 17beta-oestradiol were investigated in hypo- and oligospermic males during clomiphene-citrate, administration. A significant increase was demonstrated in the serum testosterone, dihydrosterone and 17beta-oestradiol values, mainly in the first month of therapy. The steroid increase in the ejaculate was less pronounced. Measuring of 17beta-oestradiol in serum appears to be a useful parameter for estimating the stimulative effect of clomiphene citrate.

摘要

在服用枸橼酸氯米芬期间,对少精子症和弱精子症男性的血清及精浆中雄烯二酮、睾酮、双氢睾酮和17β - 雌二醇的浓度进行了研究。血清睾酮、双氢睾酮和17β - 雌二醇值显著升高,主要在治疗的第一个月。射精液中类固醇的升高不太明显。测定血清中的17β - 雌二醇似乎是评估枸橼酸氯米芬刺激作用的一个有用参数。

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