Wieland C, Kleibel F, Weischedel U
Strahlentherapie. 1980 Jun;156(6):409-13.
42 patients with metastases to the lung and 7 patients with metastases to the liver received a combined treatment with polychemotherapy and local gamma-irradiation simultaneously. Radiation doses to the lung were mostly 15 Gy in 12 days up to 18 Gy in 2 1/2 weeks (657 to 731 ret). Right and left lung were never treated at the same time. Thus, treatment results could be compared and severe side effects were avoided. Regression of metastases occurred more often after a combined treatment, and remission lasted longer. Pneumonitis was seen in 1/3 of all cases but could be managed satisfactorily by antiphlogistics. Metastases to the liver, too, responded well to a combined treatment.
42例肺转移患者和7例肝转移患者同时接受了多药化疗和局部伽马射线照射的联合治疗。肺部的放射剂量大多为12天内15戈瑞，最高可达2.5周内18戈瑞（657至731伦琴）。左右肺从未同时接受治疗。因此，可以比较治疗结果并避免严重的副作用。联合治疗后转移灶的消退更常见，缓解持续时间更长。在所有病例中有三分之一出现了肺炎，但通过抗炎药物可以得到满意的处理。肝转移对联合治疗也反应良好。
