Shemchuk A S, Ivanova N O
Vopr Onkol. 1980;26(9):48-52.
Under study was the functional state of erythrocytes and hemoglobin in 57 patients with cancer of the cardia during the combined therapy, including preoperative gamma-radiation and surgery. The following tests were employed: the total hemoglobin content (Hb), the number of erythrocytes, hematocrit (Ht), average content and concentration of Hb in an erythrocyte, the level of fetal Hb, acid erythrograms, the reaction of transhemination, catalase and peroxidase activity, the erythrocyte volume. It was found that the patients examined developed anemia, associated with the reduced acid resistance of erythrocytes and a delayed rate of oxygen delivery to the tissues. Preoperative telegamma therapy renders preoperatively (the initial 24--48 hours) no appreciable effect on the condition of erythrocytes and Hb function. Postoperatively, greater shifts were noted in patients subjected to radiation therapy. There is an increased content of Hb, Ht, fetal Hb, average content and concentration of Hb in erythrocytes, an enhanced reaction of transhemination.
对57例贲门癌患者在包括术前γ射线放疗和手术在内的综合治疗期间的红细胞和血红蛋白功能状态进行了研究。采用了以下检测方法：总血红蛋白含量（Hb）、红细胞数量、血细胞比容（Ht）、红细胞内Hb的平均含量和浓度、胎儿血红蛋白水平、酸性红细胞图谱、转血红素反应、过氧化氢酶和过氧化物酶活性、红细胞体积。结果发现，所检查的患者出现了贫血，这与红细胞耐酸性降低以及氧气输送到组织的速率延迟有关。术前γ射线治疗在术前（最初24 - 48小时）对红细胞状况和Hb功能没有明显影响。术后，接受放疗的患者出现了更大的变化。血红蛋白、血细胞比容、胎儿血红蛋白、红细胞内Hb的平均含量和浓度增加，转血红素反应增强。
