Brown E, Freedman S, Arbeit R, Come S
Am J Med. 1980 Oct;69(4):624-7. doi: 10.1016/0002-9343(80)90478-7.
Invasive aspergillosis generally occurs in patients with hematologic malignancies, neutropenia or other severe derangements of host defense. An adult patient without such a predisposition, and without a previous history of susceptibility to infections, had rapidly progressive respiratory failure associated with repeated growth of Aspergillus fumigatus on culture of sputum and bronchoscopy specimens. At autopsy he proved to have invasive pulmonary aspergillosis.
侵袭性曲霉病通常发生在血液系统恶性肿瘤、中性粒细胞减少症或其他严重宿主防御功能紊乱的患者中。一名成年患者没有此类易患因素，也没有既往感染易感性病史，却出现了快速进展的呼吸衰竭，痰培养和支气管镜检查标本中反复培养出烟曲霉。尸检证明他患有侵袭性肺曲霉病。
