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盲法催产素激惹试验与围产期结局

Blind oxytocin challenge test and perinatal outcome.

作者信息

Staisch K J, Westlake J R, Bashore R A

出版信息

Am J Obstet Gynecol. 1980 Oct 15;138(4):399-403. doi: 10.1016/0002-9378(80)90136-2.

Abstract

A total of 435 oxytocin challenge tests (OCT) were performed on 217 high-risk pregnant patients, and the test results were blinded. The results were correlated with late decelerations of the fetal heart rate during labor, Apgar scores at 5 minutes, a neonatal morbidity score, and perinatal mortality. The incidence of late decelerations during labor was 17% in the negative group, 24% in the suspicious group, and 33% in the positive group. The correlation of OCT results and the various measures of fetal outcome indicated that an individual fetus at risk cannot be identified with a high degree of accuracy since 67% of the tests were false positive and 17% were false negative. Even when the OCT was positive, 61% of infants did not have late decelerations in labor, low Apgar scores, or significant neonatal morbidity. When elective delivery has been decided upon after consideration of all clinical information, induction of labor rather than primary cesarean section is usually indicated. In this study 78% of patients were delivered vaginally with no significant increase of cesarean sections in the positive and suspicious groups as compared with the negative group.

摘要

对217例高危孕妇共进行了435次催产素激惹试验(OCT),试验结果采用盲法。将结果与产程中胎儿心率晚期减速、5分钟阿氏评分、新生儿发病率评分及围产期死亡率进行关联分析。阴性组产程中晚期减速的发生率为17%,可疑组为24%,阳性组为33%。OCT结果与各种胎儿结局指标的相关性表明,由于67%的试验为假阳性,17%为假阴性,因此无法高度准确地识别单个有风险的胎儿。即使OCT为阳性,61%的婴儿在产程中没有晚期减速、阿氏评分低或明显的新生儿发病率。在综合考虑所有临床信息后决定择期分娩时,通常建议引产而非直接剖宫产。在本研究中,78%的患者经阴道分娩,与阴性组相比,阳性组和可疑组的剖宫产率没有显著增加。

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